Publications

Lopes D*, Denk F*, McMahon SB (2017). The Molecular Fingerprint of Dorsal Root and Trigeminal Ganglion Neurons. Front. Mol. Neurosci. https://doi.org/10.3389/fnmol.2017.00304

Lunn TH, Dawes JM, Denk F, Bennett DL, Husted H, Kehlet H, McMahon SB (2017). Preoperative ultraviolet B inflammation in skin: Modelling individual differences in acute postoperative pain and neuro-immune interactions. Eur J Pain. https://www.ncbi.nlm.nih.gov/pubmed/28913854

Denk F, Bennett DL, McMahon SB (2017). Nerve Growth Factor and Pain Mechanisms. Annu Rev Neurosci 40. https://www.ncbi.nlm.nih.gov/pubmed/28441116

Vargas-Caballero M*, Denk F*, Wobst HJ*, Arch E, Pegasiou CM, Oliver PL, Shipton OA, Paulsen O, Wade-Martins R (2017). Wild-Type, but Not Mutant N296H, Human Tau Restores Aβ-Mediated Inhibition of LTP in Tau−/− mice. Front Neurosci 11(201). http://journal.frontiersin.org/article/10.3389/fnins.2017.00201/full

Lopes DM, Denk F, Chisholm KI, Suddason T, Durrieux C, Thakur M, Gentry C, McMahon SB (2017). Peripheral inflammatory pain sensitisation is independent of mast cell activation in male mice. Pain, doi: 10.1097/j.pain.0000000000000917. https://www.ncbi.nlm.nih.gov/pubmed/28394852

Denk F (2017). Don't let useful data go to waste. Nature 543(7643):7. http://www.nature.com/news/don-t-let-useful-data-go-to-waste-1.21555

Denk F, McMahon SB (2017). Neurobiological basis for pain vulnerability: why me? Pain, in press. https://www.ncbi.nlm.nih.gov/pubmed/28129218  

Wobst HJ*, Denk F*, Oliver PL, Livieratos A, Taylor TN, Knudsen MH, Bengoa-Vergniory N, Bannerman D, Wade-Martins R (2017). Increased 4R tau expression and behavioural changes in a novel MAPT-N296H genomic mouse model of tauopathy. Sci Rep:43198. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324134/

Denk F, Crow M, Didangelos A, Lopes DM, McMahon SB. Persistent alterations in microglial enhancers in a model of chronic pain (2016). Cell Reports 15, 1-11. http://www.cell.com/cell-reports/pdf/S2211-1247(16)30507-1.pdf

Denk F, Ramer L, Erskine EL, Nassar MA, Bogdanov Y, Signore M, Wood JN, McMahon SB, Ramer MS (2015). Tamoxifen induces cellular stress in the nervous system by inhibiting cholesterol synthesis. Acta Neuropathol Commun 3(1): 74. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660723/

Crow M, Khovanov N, Kelleher J, Sharma S, Grant A, Bogdanov Y, Wood JN, McMahon SB, Denk F (2015). HDAC4 is required for inflammation-associated thermal hypersensitivity. FASEB 29(8): 3370-3378. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511203/

Thakur M, Crow M, Burden N, Davey G, Levine E, Kelleher JH, Agley C, Denk F, Harridge S, McMahon SB (2014). Defining the nociceptor transcriptome. Front Mol Neurosci 7: 87. http://journal.frontiersin.org/article/10.3389/fnmol.2014.00087/full

Denk F, McMahon SB, Tracey I (2014). Pain vulnerability: a neurobiological perspective. Nat Neurosci 17(2): 192-200. http://www.nature.com/neuro/journal/v17/n2/abs/nn.3628.html

Denk F, Huang W, Sidders B, Bithell A, Crow M, Grist J, Sharma S, Ziemek D, Rice AS, Buckley NJ, McMahon SB (2013). HDAC inhibitors attentuate the development of hypersensitivity in models of neuropathic pain. Pain 154(9): 1668-79. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763368/

Crow M, Denk F, McMahon SB (2013). Genes and epigenetic processes as prospective pain targets. Genome Med 5(2): 12. https://genomemedicine.biomedcentral.com/articles/10.1186/gm416

Denk F, McMahon SB (2012). Chronic pain: emerging evidence for the involvement of epigenetics. Neuron 73(3): 435-44. http://www.sciencedirect.com/science/article/pii/S0896627312000943

Shipton OA, Leitz JR, Dworzak J, Acton CE, Tunbridge EM, Denk F, Dawson HN, Vitek MP, Wade-Martins R, Paulsen O, Vargas-Caballero M (2010). Tau protein is required for amyloidβ-induced impairment of hippocampal long-term potentiation. J Neurosci 31(5): 1688-92. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836238/

Denk F, Wade-Martins R (2009). Knock-out and transgenic mouse models of tauopathies. Neurobiol Aging 30(1): 1-13. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806682/

Boothman L, Raley J, Denk F, Hirani E, Sharp T (2006). In vivo evidence that 5-HT(2C) receptors inhibit 5-HT neuronal activity via a GABAergic mechanism.  Br J Pharmacol 149(7): 861-9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014685/

Denk F, Walton ME, Jennings KA, Sharp T, Rushworth MF, Bannerman DM (2005).  Differential involvement of serotonin and dopamine systems in cost-benefit decisions about delay or effort. Psychopharmacology 179(3): 587-96. https://www.ncbi.nlm.nih.gov/pubmed/15864561